Aterosclerose obliterante periférica: epidemiologia, fisiopatologia, quadro clínico e diagnóstico. In: Maffei FHA, editor. Doenças vasculares periféricas. Palavras-chave: homocisteína, aterosclerose, doenças vasculares. .. Aterosclerose obliterante periférica: epidemiologia, fisiopatologia, quadro clínico e. Palavras-chave: Claudicação intermitente, aterosclerose, terapia por exercício, .. Maffei FHA, Lastória S. Aterosclerose obliterante periférica: epidemiologia.

Author: Mejinn Jubar
Country: Chile
Language: English (Spanish)
Genre: Environment
Published (Last): 2 August 2016
Pages: 371
PDF File Size: 10.19 Mb
ePub File Size: 11.76 Mb
ISBN: 257-6-81603-806-9
Downloads: 79631
Price: Free* [*Free Regsitration Required]
Uploader: Tojagul

The animals were monthly weighed since the day previous to the treatment. J Intern Med ; An observational, retrospective, cohort study of consecutive series of cases was performed in claudicating patients receiving care at a specific outpatient clinic of vascular surgery in our institution from January through March Exercise for intermittent claudication.

Oclusão Arterial Aguda e Crônica by Marília Ito on Prezi

All these perigrica of homocysteine taken together are named total homocysteine or plasma homocysteine. Patients with major amputations and prosthesis who had not been totally rehabilitated or had rehabilitation difficulties were also part of this group. The authors also considered that vitamin supplementation with folic acid was beneficial, cost-effective and could be perifric as an adjuvant therapy for patients with symptomatic or asymptomatic atherosclerosis.

Figure 2 – Digital photograph of the anterior luminal surface of the aortic arch longitudinally opened and stained with Sudan IV in animals that were given hypercholesterolemic diet.

In vitro studies with endothelial cells in culture evidenced that auto-oxidation of homocysteine in plasma would produce oxygen-derivative species, including hydrogen superoxide and peroxide, which would be associated with vascular toxicity, proliferation of smooth muscle cells and oxidation of low-density lipoprotein LDL cholesterol.

In our series, we observed that although obbliterante with asymptomatic CD only accounted for 5.


Cardiac complications in vascular surgery Complicações cardíacas em cirurgia vascular

From This Paper Figures, tables, and topics from this paper. Showing of 21 references.

However, the relation of this finding with plasma homocysteine levels was not studied yet. The major part is in the form of homocystine a disulfide oxidation product of homocysteinehomocysteine-cysteine mixed disulfide and protein-bound homocysteine specially albumin.

Infrapopliteal angioplasty: the more arteries are treated the better?

Services on Demand Journal. A total of procedures were conducted, because six patients underwent surgery in two different territories concomitantly. After a h fasting, 18 venous blood was collected from the marginal vein of the right ear in 6 ml bottles with anticoagulant for dosage of the lipid profile. Mean follow-up time was Due to the importance of this disease for human beings, researchers have been continuously searching for experimental models to better characterize it.

Br J Surg ; Mortality over a period of 10 years ategosclerose patients with peripheral arterial disease. Unique efficacy of methionine metabolism in premenopausal women may protect against vascular disease in reproductive years. Cardiac effects of prolonged and intense exercise training in patients with coronary artery disease. This assessment was called treadmill claudication distance.

Management of peripheral arterial disease and intermittent claudication.

Coronary disease was not predictive of death among patients who underwent major peripheral vascular surgery. The pathogenesis of atherosclerosis: Therefore, according to this analysis, mortality was probably more related to non-performance of exercises than to presence of other risk factors. Prevalence of PAD increases with age, and is more prevalent in the age ateroaclerose between years. Plasma homocysteine as a risk factor for vascular disease.

The demographic data and comorbidities can be seen in Table 1. He obtained atherosclerosis only in the rabbits fed with egg yolk and concluded that cholesterol was the atherogenic factor present in obluterante egg yolk. On the other hand, the patients with limitations to perform the walking program as recommended did not have the previously mentioned advantages, which might eventually contribute to lower survival rates.


Cutting balloon angioplasty of the popliteal and infrapopliteal vessels for symptomatic limb ischemia. In vitro studies in cells exposed to homocysteine evidenced an increase in coagulation factors XII and V, reduction in protein C activation, inhibition of tissue plasminogen activator, reduction in bioavailability of nitric oxide and prostacyclin, inhibition of platelet aggregation, increase in activity of von Willebrand factor, inhibition of thrombomodulin expression, induction of tissue factor expression and suppression of heparin sulfate expression in the vascular wall.

There was no macroscopic change in the evaluated arterial segments of control group animals, before and after histochemical analysis of fat. It should be stressed the formation of macroscopic lesions induced only by diet, reaffirming that hypercholesterolemia is sufficient for atherogenesis. There was increase in concentration of total cholesterol and fractions in the group receiving diet supplemented with egg yolk, but there was no difference perlfrica levels of triglycerides between the groups.

Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. Comparative study of evaluation and outcome of patients with intermittent claudicating, with or without limitation for exercises, followed in specific out-patient setting.

Homocyst e ine and arterial occlusive diseases.